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KMID : 0357919820160040856
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Korean Journal of Pathology
1982 Volume.16 No. 4 p.856 ~ p.859
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Pancreatoblastoma -A case report with electron microscopic examination-
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Abstract
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A ease of infantile carcinoma of the head of pancreas specifically diagnosed as
pancreatoblastoma was presented in a 4-year-old Korean boy.
A well encapsulates intra-abdominal mass was found which was attached to the
ventral aspect of the pancreatic head, covered by the lesser omentum anteriorly, and
was predominantly cystic.
Histologic examination revealed that the tumor was made up largely of cuboidal to low
columnar epithelial cello arranged in acinar or tubular structures and solid sheets, and of
a few islands of squamoid cells with elongated nuclei arranged in a parallel fasciculating
pattern (squamoid corpuscles).
Ultrastructural examination of the acinar or tubular strictures stowed microvilli on the
luminal surface, well developed granular endoplasmic reticulum, and electron dense
zymogen-like granules especially at the apical portion of the cytoplasm. The tumor cells
of squamoid corpuscles had tonofilaments and few zymogen-like granules. These
findings strongly support the view that pancreatoblastoma arises from cells which might
ultimately differentiate into exocrine acinar cells of the pancreas.
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